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Gezond weefsel beter sparen Dat is het voordeel van protonentherapie.

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Research

Research

How HollandPTC works to enhance the benefits of proton therapy

 

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HollandPTC

HollandPTC

Voor de beste protonentherapie van nu en later

Over HollandPTC
Onze visie: Samen beter, beter samen Ons team HollandPTC software
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SAMEN BETER, BETER SAMEN

Patiënten

Patientenzorg

Gezond weefsel beter sparen Dat is het voordeel van protonentherapie.

Bekijk
Over de behandeling Waarom protonentherapie Algemene informatie Soorten kanker Ervaringen van patiënten Tips en adviezen Second opinion Jongvolwassen en kanker Lopende studies
Uw bezoek aan HollandPTC Locatie en contactgegevens Wat neemt u mee Vervoer en overnachten Compliment of klacht
Praktische informatie Vergoeding van uw behandeling Uw dossier Patiëntenervaringen
Research

Research

How HollandPTC works to enhance the benefits of proton therapy

 

View
Research at HollandPTC Research projects Organisations & collaborations Our researchers Publication list
Facilities Pre-clinical and clinical facilities Our research database: how to request data Doing proton research or use our facilities
Practical information Practical information on Varian projects R&D communication box
HollandPTC

HollandPTC

Voor de beste protonentherapie van nu en later

Over HollandPTC
Over HollandPTC Onze visie: Samen beter, beter samen Ons team HollandPTC software
Cliëntenraad HollandPTC foundation Diversiteit en gelijkheid Contact

AUTOPT: Fully-automated multi-criterial planning for intensity-modulated proton therapy (IMPT) for clinical practice

 

Principle Investigators: Prof. dr. Coen Rasch (LUMC), Prof. dr. Ben Heijmen (Erasmus MC)

PhD students: Merle Huiskes (LUMC),  W. Kong (Erasmus MC)

Funding: HollandPTC-Varian 2019

Description

Treatment plan generation for intensity-modulated proton therapy (IMPT) is highly complex, especially if it includes selection of favourable beam geometries. Currently, treatment plans are generated in an iterative trial-and-error procedure (‘manual planning’). Each iteration is time-consuming, which severely restricts the total number of iterations that can be performed for an individual patient, risking sub-optimal quality of the final plan. This quality is also dependent on the experience and subjective choices made by the manual planners. To mitigate as much as possibly issues with plan quality, the current manual planning in proton therapy centres is unavoidably associated with a high workload.

This project develops and investigates fully-automated, multi-criterial and robust planning for IMPT for clinical use. As a starting point and core application for the investigations we will use the iCycle optimizer which has been extensively studied and validated for automated treatment planning (autoplanning) for photon beams. Options for integrated computerized beam angle selection for IMPT, taking into account robustness requirements, will be added to iCycle.